Palermo welcome Sampdoria to the Stadio Barbera on their return to Serie A on Sunday evening at 2045 local time.
The home side, and Serie B champions, are led by youngster Paulo Dybala with Stefano Sorrentino a surprising choice between the sticks as he looks set to leave the club.
Sinisa Mihajlovic is giving former Palermo goalkeeper Emiliano Viviano his Serie A debut for his new club, while Gianluca Sansone, Eder and Stephan Okaka line up up front.
Palermo (3-5-2): Sorrentino; Munoz, Terzi, Andelkovic; Pisano, Bolzoni, Rigoni, Barreto, Daprelà; Vazquez, Dybala.
Sampdoria (4-3-3): Viviano; De Silvestri, Gastaldello, Regini, Cacciatore; Soriano, Palombo, Obiang; Sansone, Okaka, Eder.