The 29-year-old Brazilian has fallen down the pecking order at the La Liga club since the return of Felipe Luis from Chelsea, with boss Diego Simeone accepting the player wants to leave the club in search of first team football.
Sky Sport Italia are reporting that Inter have made contact with Atletico about a possible transfer, and expect an answer in the coming days.
Inter coach Roberto Mancini has identified the full-back slot as a weak point in the Nerazzurri squad and has also checked on the availability of Napoli defender Faouzi Ghoulam.
Siqueira made 25 appearances for the Colchoneros last season following his arrival from Granada for a fee in the region of €10 million.
