Palermo welcome Sampdoria to the Stadio Barbera on their return to Serie A on Sunday evening at 2045 local time.
The home side, and Serie B champions, are led by youngster Paulo Dybala with Stefano Sorrentino a surprising choice between the sticks as he looks set to leave the club.
Sinisa Mihajlovic is giving former Palermo goalkeeper Emiliano Viviano his Serie A debut for his new club, while Gianluca Sansone, Eder and Stephan Okaka line up up front.