In a scintillating first half which was curtailed for Paolo Cannavaro after ten minutes with a thigh injury and was replaced by Luca Antei, Juventus thought they had taken the lead when Leonardo Bonucci netted but was ruled out for offside.
The half really burst into life when Simone Zaza scored after 13 minutes when a goal line clearance was Alessandro Longhi header found Zaza who eventually fired in from eight yards.
It only took six minutes for parity to be restored when Carlos Tevez found Paul Pogba on the edge of the Sassuolo box and the Frenchman hit an unstoppable shot for his first of the season.
Chances came for La Vecchia Signora as they pressed high looking to win the ball early and Pogba nearly netted his second after a weaving run through the Neroverdi defence brought out a great save from Andrea Consigli who then saved the rebound from Tevez.
The second half continued in the same vain with Juventus in control but the pace of Zaza a threat, a Domenico Barardi free kick for which Pogba was booked for conceding went inches wide and then Berardi crossed a minute later but Antei headed wide.
Juventus coach Massimiliano Allegri then made a formation change when replacing Patrice Evra for Claudio Marchisio and went to a 4-3-3 to try and find a breakthrough.
Marchisio almost had an instant impact when he shot wide but moments later Zaza stung the palms of Gianluigi Buffon on a quick break.
The disappointing Fernando Llorente was replaced by Kingsley Coman, Tevez with his direct running still causing problems for the ever Sassuolo defence who were dropping ever deeper and Pogba failed to take advantage when he shot wide after a weaving run from the Argentinian.
Consigli in the Sassuolo goal looked comfortable with most of what was being asked but should have been beaten when Coman’s swivel shot wide wide.
Finishing the game with a back five, the bottom side held on for a valuable and memorable point.