Having won under now first team coach Filippo Inzaghi last year, they took on PSV Eindhoven in the opener and did get themselves in front in the match when Michael Fabbro headed them into the lead after 19 minutes.
But goalkeeper Gianluigi Donnarumma, brother of Genoa’s Antonio and not yet 16, came in for criticism in the part he played in allowing the Dutch side in for victory thanks to a Ryan Hiwat brace in the second half.
Cristian Brocchi’s side will look to rebound on Wednesday when they face Palermo. The Rosanero had no such problems in their first game as they swept Apia Leichhardt aside, Antonio La Gumina scoring twice.
Tiziano Tulissi got the winner for Atalanta as they squeezed past Bruges while Bari put three past Vicenza without reply in their game and a goal from Mattia Persano put Napoli on their way to a 3-1 success against Pakhtakor.
Hellas Verona were 1-0 winners in their tournament opener while Fiorentina needed Andy Bungu’s 93rd minute winner to see of Nordsjaelland 3-2.
In the final game, Cesena were beaten 4-2 by Cremonese.