Inter, who are aiming to add another attacking option to their new-look squad.
The 28-year-old made a strong impression within the Blucerchiati forward line last season, leading to his first call-up to the Italian national team.
According to La Gazzetta dello Sport, the Nerazzurri have placed an €8.5 million bid on the table during a meeting between officials from both sides.
Il Doria president Massimo Ferrero has been reluctant to strike a deal thus far, but a second negotiation is scheduled and now it is up to Samp patron to ponder the offer more closely.
Brazilian born star Eder scored 9 goals in 30 Serie A appearances last term, whilst featuring in a variety of positions including left wing and central striker.
