Juventus denied him permission, a decision that the striker is disappointed to hear about.
The ambitious youngster had been keen to travel to Brazil in August to compete for his nation in the Olympic Games, but the timing of the event presents problems for Juventus who would want him to be involved in pre season training at that point.
“I will not go to the Olympics,” he informed fans upon arriving in Buenos Aires on Monday.
“It isn’t a personal choice of mine, Juventus didn’t give me permission.”
Argentina are looking to scoop their third gold medal in four attempts this summer, after losing out to Mexico in 2012 in London, but will now be looking at who to replace Dybala with.
“I’m sorry because I care a lot about playing for my country,” the forward continued.
“If I could choose, then I’d definitely go to Rio.”