Napoli (4-3-3): Meret; Di Lorenzo, Manolas, Koulibaly, Ghoulam; Fabian Ruiz, Demme, Zielinski; Callejon, Mertens, Insigne.
Roma (4-2-3-1): Mirante; Zappacosta, Mancini, Smalling, Kolarov; Cristante, Veretout; Kluivert, Lo. Pellegrini, Mkhitaryan; Dzeko.
Unavailable: Juan Jesus, Lopez.
– Napoli and Roma have met 145 times so far in Serie A: the Giallorossi lead by 52 wins to 43, with 50 draws.
– Roma won the reverse fixture in November 2019 (2-1) – last time they won both meetings against Napoli in the same Serie A campaign was in 1997/98, under Zdenek Zeman.
– Napoli’s last win at the San Paolo against Roma was in November 2014 (2-0 under Rafa Benítez); since then, they’ve picked-up just two points from four games at home against the Giallorossi.
– After losing four home games in a row, Napoli have won three of their last four Serie A games at the San Paolo (L1).
– Napoli have lost each time they’ve been trailing at home in this Serie A campaign.
– Gennaro Gattuso is unbeaten as a coach against Roma in the top flight (W2 D1).
– Matteo Politano’s first Serie A goal was against Roma in September 2015, when he was at Sassuolo.
– After failing to score in his first four Serie A appearances against Roma, Dries Mertens has managed to score in his last two games against the Giallorossi at the San Paolo.
– Roma’s striker Edin Dzeko has scored four goals in four appearances at the San Paolo (two braces).