Roberto Mancini’s Azzurri sit top of League A Group 1 after three games, sitting on five points. The Dutch, meanwhile, are a point behind in second, level on four points with Poland.
Wednesday’s game will see two Dutch players enjoy something of a homecoming as Hans Hateboer and Marten de Roon will be playing at their own club’s stadium in Bergamo.
Italy: Donnarumma; D’Ambrosio, Bonucci, Chiellini, Spinazzola; Barella, Jorginho, Verratti; Chiesa, Immobile, Pellegrini
Netherlands: Cillessen; Hateboer, de Vrij, Van Dijk, Ake, Blind; Van de Beek, F de Jong, Wijnaldum; L de Jong, Depay