A dreadful performance saw the Bianconeri comprehensively beaten, with Trevor Chalobah, Reece James and Callum Hudson-Odoi giving Chelsea a commanding lead.
Timo Werner tapped in with only minutes remaining after a Weston McKennie error to condemn Juventus to their heaviest defeat in the competition.
Szczesny 5.5; Cuadrado 4.5 (’80 De Winter N/A), Bonucci 5.5, De Ligt 5, Alex Sandro 4.5; McKennie 4.5, Bentancur 4 (’58 Dybala 5.5), Locatelli 5 (’67 Arthur 5), Rabiot 4; Chiesa 4.5 (’80 Kulusevski N/A), Morata 5.5 (’67 Kean 5.5)
Player of the match: Wojciech Szczesny
The Poland goalkeeper did not cover himself in glory and wasn’t much better than his beleaguered teammates, but some smart saves in the first half prevented this from being even more of a humiliation for Juventus. He did well to keep out a Reece James freekick before the break, and reacted quickly to deny Hakim Ziyech late on.